Questions tagged [splicing]

Splicing is a modification of an RNA after transcription, in which intervening nucleotide sequence sequences (introns) are removed and the remaining sequences (exons) are joined.

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What percentage of introns are spliced in polyadenylated mRNAs?

I am asking a variation of a previously asked question: What percentage of RNA splicing happens during transcription? I am planning mRNA purification using poly(A) antisense-oligo pull-down and, for subsequent purposes, would need to have an…
KaPy3141
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Why do organisms not just have more genes to account for the possible gene products generated from alternative splicing?

Alternative splicing can generate many gene products from single genes, by combinatorial inclusion / exclusion of introns / gene segments. What is the evolutionary advantage of having a complex processing system that allows for alternative splicing,…
Noah Harrison
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