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Questions tagged [epigenetics]

Mechanisms for inheriting phenotype outside of the genomic DNA sequence.

Often refers to at sites.

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Transmission of epigenetic regulation through surrogate mother

I know the basics of epigenetics, but I do not know how epigenetic mechanisms are transmitted from parents to children (or if there is even enough literature to derive a consensus). My question is relates to surrogate motherhood, in which an egg is…
Daniel Standage
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Defining paper(s) in epigenetics

For someone who is interested in learning about the discovery of epigenetics, which are the foundational defining papers in the area?
Daniel Standage
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What are the criteria for determining the influence of epigenetic factors?

Isolating a gene or sets of genes in diseases sometimes isn't enough to determine penetrance - epigenetic factors can have a significant effect. What are the criteria in determining whether epigenetic factors are significant?
ghchinoy
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Are prions an important driver in evolution?

I understand that prions have been implicated in the passing on of epigentic information[1]. Are prions thought to play a significant role in the evolution of organisms? Alberti S, Halfmann R, King O, Kapila A, Lindquist S. 2009. A systematic…
Poshpaws
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why nucleosome spacing is longer in heterochromatin than euchromatin

Heterochromatin is defined as tightly packed form of DNA. But some experiments show that the average spacing of nucleosomes associated with H3K9me3 and H3K27me3, both heterochromatin marks, are longer than those with euchromatin marks. why packed…
Kun
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Can the SAME histone tail have both H3K4me3 and H3K27me3?

I'm studying bivalent promoters and enhancers. I understand that the same region of genome can have both H3K4me3 and H3K27me3. But can they occur on the same histone tail? Please provide me with a reference to support your answer.
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Can epigenetics have positive impact on the genes are development?

I know that epigenetics have capacity to affect and degrade the genes thereby inducing problems/illness/degradation in body functions. Can they also make better genes or have positive impact on genes or body? If yes, can someone give some examples?
Gissipi_453
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Epigenetic marks

I was lately researching epigenetics and the current research on age reversal. Because epigenetic processes are influenced by the environment and can vary over time, I wanted to know if all epigenetic marks and mechanisms, including those that play…
AIA
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