Quantitative genetics is the study of inheritance at the phenotypic level.
Many of the phenotypic traits we can observe are affected by more than one gene. Traits affected by many genes are called quantitative, metric, or polygenic traits.
Questions tagged [quantitative-genetics]
43 questions
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More extreme phenotypes when parents are from diverged populations
In quantitative traits we have many loci affecting a trait. If we took a bunch of parents where all mothers and fathers were of a certain value at the upper end of a trait range, and then looked at the offspring would we expect offspring from pairs…
rg255
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dominance coefficient, why (1+k)?
I'm trying to get a better understanding of quantitative genetics by reading Lynch and Hill 1986. I'm getting stuck with some notation that's used right at the beginning referring to the mutant and WT alleles at a given loci.
2ai is the genotypic…
petersoapes
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Loss of allelic variation per generation of full-sib mating
If we take a male and female, cross them, and collect one son and one daughter to produce the next generation (and continually do this for many generations) - (full-sib mating design) how much genetic variance is lost per generation/how do we…
rg255
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Additive genetic variance $V_A= 2pqa^2$ ... what is $a$?
Reading Falconer and Mackay looking at equation $V_A = 2pqa^2$ (equation 8.5, page 126).
I am trying to write a clear explanation of how additive genetic variance is defined and calculated, but I keep getting twisted up in the books I am working…
rg255
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