C1orf38
Chromosome 1 open reading frame 38 is a protein that in humans is encoded by the C1orf38 gene.[5] The gene is also known as ICB-1 and THEMIS2 in humans, and the orthologue in mice is BC013712.[5] C1orf38 has been associated with cancer susceptibility.[6]
| THEMIS2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | THEMIS2, C1orf38, ICB-1, thymocyte selection associated family member 2, ICB1, Chromosome 1 open reading frame 38 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617856; MGI: 2446213; HomoloGene: 21009; GeneCards: THEMIS2; OMA:THEMIS2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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References
- GRCh38: Ensembl release 89: ENSG00000130775 – Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000037731 – Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Chromosome 1 open reading frame 38". Retrieved 2011-12-07.
- Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O (July 2009). "Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility". Cancer Investigation. 27 (6): 669–672. doi:10.1080/07357900802620877. PMID 19308812. S2CID 205570175.
Further reading
- Haselberger M, Springwald A, Konwisorz A, Lattrich C, Goerse R, Ortmann O, et al. (July 2011). "Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells". International Journal of Molecular Medicine. 28 (1): 121–127. doi:10.3892/ijmm.2011.663. PMID 21455565.
- Springwald A, Lattrich C, Skrzypczak M, Goerse R, Ortmann O, Treeck O (November 2010). "Icb-1 Gene expression is elevated in human endometrial adenocarcinoma and is closely associated with HER2 expression". Cancer Investigation. 28 (9): 904–909. doi:10.3109/07357907.2010.483511. PMID 20569072. S2CID 35017943.
- Konwisorz A, Springwald A, Haselberger M, Goerse R, Ortmann O, Treeck O (March 2010). "Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells". Endocrine-Related Cancer. 17 (1): 147–157. doi:10.1677/ERC-09-0095. PMID 19942713.
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