Biology Stack Exchange
Biology Stack Exchange

Questions tagged [human-genetics]

The scientific study of inheritance as it occurs specifically in human beings.

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How it is determined that a particular gene or set of genes is responsible for a trait?

How it is determined that a particular gene or set of genes is responsible for a trait? Is it just a statistical analysis of people showing and not showing the trait and the genes they have (or don't have) and their variants (alleles)? Or, there is…
akm
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Cause of hexadactylisim in Amish people

Is it caused by inbreeding of many generations within an isolated population?
txn
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What is the criterion for genetic similarity among siblings and humans in general?

I just started reading Blueprint by Robert Plomin. He makes some well-known statements about genetic similarity which we all have read somewhere but I would like to know what the criteria for genetic similarity actually are: He writes that all…
Maximilian
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What is a Mitochondrial Eve and Y-chromosomal Adam

I've read this question: What kind of event would cause the current Mitochondrial Eve to be replaced by a new one? And the values in Wikipedia about Mitochondrial Eve and Y-chromosomal Adam and I am not sure I understand the concept behind…
SIMEL
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What is the right definition of 'Sex Linkage'?

I am confused about definition of "sex linkage". I have found different definitions but they do no match. From P.S Verma, V.K Agarwal cell biology, genetics, molecular biology, evolution and ecology: If the genes are situated in the same chromosome…
Khan
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Regeneration capabilities in humans?

To what extent can humans, (mammals in general), theoretically regenerate, and is their a way to speed up and/or exceed this original extent.
Erik Redburn
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In our 23 chromosome pairs, do the 2 members of the pair have distinct or virtually identical sequences?

I understand that we have 46 DNA molecules in the nucleus of our cells, arranged in 23 pairs: 22 autosomal and 1 sex chromosome pairs. I have read in different sources that the pairs contain nearly identical members, excluding any mutations. I have…
Stephen
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Is there variation in which olfactory receptor genes are functional in humans?

According to wikipedia humans have around 400 functional olfactory receptor genes and 600 pseudo genes. Most mammals have higher numbers of functional OR genes. My question is whether it has been studied how the number or subset of these functional…
BlindKungFuMaster
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Are human males and females more genetically different than members of other species?

I'm looking at this Ted talk about a Saudi Arabia woman who dared to drive a car in the last few years. This reminds me that until the last century or so, women (all over the world?) enjoyed less rights and might've been pigeonholed into roles…
Alex Stone
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Is Gorlin's sign hereditary?

"Gorlin's Sign" is the ability to touch the tip of the nose with the tongue. It is present in half of people with Ehlers-Danlos syndrome, but is also present in a minority of people without that disorder: among them, both me and one of my sons. Is…
feetwet
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What percentage of people today would likely be descendants a man born 4,000 years ago?

Assuming a particular man was born in southern Mesopotamia, around 4,000 years ago, and was significant involved in a major religion. To what degree (if any) of accuracy could his descendants be traced? What percentage of the global population is…
James Jenkins
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What is meant by translational repression by an upstream open reading frame?

The NCBI report on the human huntingtin gene contains the following statement: “This gene contains an upstream open reading frame in the 5' UTR that inhibits expression of the huntingtin gene product through translational repression.” But no…
Noob
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DNA Inheritance- Math vs. Biology

After doing some statistical analysis of the raw math involved in DNA contributions, I would like to understand the scale of the biological factors. I know that 99% of the human genome is identical in all human beings, so genetic recombination and…
Joseph Filip
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Figure out which is the risk allele from SNP in GWAS article

I do neuroimaging research, and am interested in dabbling in genetics. I am trying to create an anxiety risk profile score from several SNPs shown to correlate with measures of anxiety in past GWAS studies. However, many of the GWAS studies, such as…
user52710
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Subtracting shared DNA with half-sibling

I want to note that I am not a biologist. I've been on a nearly 20-year search for the identity of the parents of my 4th great grandfather (not an easy task.) I'm using ancestry.com DNA, GEDmatch, and family trees of my matches in hopes of using DNA…
Melanie Shebel
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