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Questions tagged [pharmacology]

Pharmacology is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function.

The study of drug action. Includes toxicology and drug composition. May be broken into pharmacokinetic and pharamcodynamic.

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Resources for finding all drugs of a certain class

I may be embarking on a project involving a fairly extensive healthcare records data set, looking for the use of a particular type of drug (for example, "Proton Pump Inhibitors"). But these drugs are usually listed by their trade or generic names -…
Fomite
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Do drugs always degrade after they have passed their expiration date?

I have been wondering for some time whether several drugs really have an expiration date. Let's narrow the scope and think about only "common" drugs, e.g NSAIDs, antibiotics etc. For example, would antibiotics in the pills get deactivated or…
zeller
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Is there any completely Computation Drug ever launched in market?

I am working in bioinformatics(part of it in Drug Designing) for years, still if I have no idea about it. As it is too hard to prove (Pass all Clinical trials) and get FDA Approvals. So, My question is there a drug available in market, which is…
Devashish Das
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Why is methylcellulose used in pharmaceuticals?

Why is methyl cellulose used as a pharmaceutical excipient? Is it due to certain chemical properties? What are the reasons for relying on the chemical properties of methyl cellulose?
Thunder
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What are the psychedelic effects of (star) anise and how many people are affected?

Backstory: My girlfriend reacts heavily to chocolate and drinks containing stellar anise, in a way that seems comparable to psychedelic drugs. After consuming it, it takes approximately five minutes for the reaction to become apparent. Observed…
Kjeld Schmidt
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What constitutes FDA's First in Class designation for New Molecular Entities?

What constitutes a First in Class designation for new molecular entities? I've seen this term on FDA documents, as well as in databases (Chembl for example), but I was curious if there are any set criteria for First in Class drugs? The easy…
heliotrope
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Compatibility drugs info

Let's suppose that I take a DrugA for ProblemA and then I got this ProblemB and started to take DrugB. Are there general rules I can look up to figure out whether I can take DrugA & DrugB simultaneously? I mean drugs can cancel each other or vice…
Stanislav Bashkyrtsev
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Can ingestion of B6 cause gastrointestinal disturbance?

Can the ingestion of vitamin B6 upset the stomach, and if so by what mechanism?
susan
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Could Racemic Epinephrine be used to Treat Anaphylaxis?

To be clear, this question is not a personal health question nor a question seeking health advice, it is only a theoretical question born of a curiosity for the pharmacology and biochemistry of adrenalin/epinephrine... I have never in my life had…
Brian
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What's the mechanism of action of Levomepromazine's analgesic effects?

I have absolutely no idea as to how Levomepromazine elicits its analgesic effects so please do direct me to journal articles and other credible sources with you, the answerer, making a summary of Levomepromazine's mechanism of action in your answer.
Josh Pinto
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Why is Paracetamol so great?

Every time I get ill (cold, flu etc) I take a couple of these wonderful tablets for up to 4 times a day and I, eventually, get better. What exactly is paracetamol? Why is it so effective and is it really not harmful as my doctor would have me…
Sachin Kainth
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What does "generalisation" mean?

I am trying to understand a paper about ethanol: "Generalisation of ethanol with drug mixtures containing a positive modulator of the GABAA receptor and an NMDA antagonist" (Stolerman & Olufsen, 2000) In the abstract it says, "After…
user22316
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How does steroid dependence occur?

I have seen on the internet that prolonged steriod treatment can result in the development of steroid drug tolerance leading to decreased hormone secretion. In turn this may lead to drug dependence, as you need to keep taking that drug to keep your…
user127595
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Preventing paracetamol overdose

Paracetamol overdose is one of the most common drug toxicities. It may be treated by intravenous N-acetylcysteine which replaces the glutathione that is used up in paracetamol metabolism to prevent the harmful effects of NAQBI. Why can glutathione,…
AndroidPenguin
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Umbrella term for agonist, antagonist, inverse antagonist, etc.

For most receptors there exist different ligands that induce different responses. Depending on the response these different ligands can be classified into different groups such as agonists, antagonists, inverse antagonist, etc. My question: is there…
Dahlai
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