In paper Mutational heterogeneity in cancer and the search for new cancer-associated genes, Figure 1 defines:
Somatic mutation frequencies observed in exomes from 3,083 tumour–normal pairs. Each dot corresponds to a tumour–normal pair, with vertical position indicating the total frequency of somatic mutations in the exome.
Is the figure representing with each point a tumor/normal pair because somatic mutations (differently from germline mutations) are assumed to not be present in the normal sample?
