So, a long time ago I asked if it was possible to convert Sculptris files into proper Blender files... with proper texture maps, are able to be baked and re-used. At best, importing the Sculptris object leaves a corrupted texturemap that only half-exists, and cannot be edited much without causing problems.
However, I have managed to find a solution that helps resolve a LOT of this.
The problem is that imported Sculptris objects retain the Sculptris texture/mapping data, which is incompatible with Blender.
All you need to do is copy the geometry and make a new object. The result is a proper BLENDER object that coincidentally has the same vertices as the import.
Keep in mind my tests have been limited; but I've managed to successfully create proper displacement maps in the UV editor using this technique when previously I could only create a UV mess, so I'm confident this resolves a lot of the issue. I haven't had a chance to experiment so thoroughly.
However, there is still an issue with textures. Please see my reply below for some possible solutions.