Observing the manual informs that it is possible to reset the projection but could not reset the position of the cursor in the UV Map.
bpy.ops.uv.cursor_set(location=(0.0, 0.0))
Location, Cursor location in normalized (0.0-1.0) coordinates
https://docs.blender.org/api/blender_python_api_current/bpy.ops.uv.html