Questions tagged [psychopharmacology]

For questions about the scientific study of the effects of pharmaceutical and general drugs on perception, behavior, mood and cognition.

For questions about the scientific study of the effects of pharmaceutical and general drugs on perception, behavior, mood and cognition.

For more information, see Psychopharmacology.

For a sense of how the field is evolving see Neuropsychopharmacology which is a movement to combine psychopharmacology with modern research on neurotransmission.

For an accessible text, see Molecular Neuropharmacology: A Foundation for Clinical Neuroscience

See also .

Please limit questions to scientific inquiries only, "self-help" questions are discouraged.

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What is the Mechanism of 5-HT2A-mediated psychedelia?

Drugs that activate the serotonergic 5-HT2A receptor (e.g. LSD, psilocybin, mescaline) are notorious for causing psychedelic experiences and I would like to know the neurochemical mechanism behind this.
Josh Pinto
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Polypharmacy involving sumatriptan, tramadol and serotoninergic antidepressants and risk of serotonin syndrome

Let us consider the following clinical vignette: A 61 y/o male presents complaining of migraines on the order of 2 or 3 times a month. When he gets them, the only thing that helps to mitigate them is a combination of Sumatriptan 100mg and Tramadol…
user18670
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Is it believed that ketamine has less side effects compared to SSRIs?

I was told that recent research shows that ketamine is equally effective to, and not more effective than, SSRIs when used as a regular medication, for example as a nasal spray. However, is it believed that ketamine has less side effects than SSRIs,…
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Is there any medication which is molecularly similar to alcohol?

I have found alcohol to have beneficial and desirable effects on me, and I have been exploring the question of why alcohol is not given the same level of pharmaceutical legitimacy as other medicines and medications. For example, is there even any…
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What medication would best treat buspirone induced insomnia?

The anxiolytic buspirone causes insomnia in a small minority of patients. What existent medication would theoretically (or in practice) best treat this insomnia? Buspirone from my understanding is an agonist of the 5-HT1A autoreceptors, has very…
JohnD
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