You may be aware of a famous story which found that Taxi Drivers as well as Super Mario 64 (3D adventure game) players showed a an increase in grey matter located in their hippocampus.
https://www.nature.com/articles/mp2013120
This (and I'm sure other, older examples and research) demonstrates that the size and/or density of certain brain regions can change as a function of its use, roughly similar to muscles; from this observation stems the questions:
Can a brain, or regions of a brain grow so large as to start pushing up against the skull?
If a specific region of the brain grows or shrinks, will the skull eventually reshape to accommodate?
Is it possible that a brain can shift in weight distribution, caused by prolific development of specific regions, to such a degree that sensitive structures in the skull, head, or neck are affected?