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Prove that $p(x)=(x-1)(x-2) \cdots (x-n) + 1$ is irreducible over $\mathbb{Z}$ for all $n \geq 1$, $n \neq 4$.

I do not clearly see how to solve this problem and what is so special about the integer $4$ here?

Thanks for your help in advance

the8thone
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