$\newcommand\R{\mathbb{R}}$Suppose that $S\subset\R$ is a
countable set of reals, and consider the complementary set $\R-S$.
Since the unit interval is uncountable and more specifically contains uncountably many disjoint countably infinite sets (e.g. small translations of the rationals in some tiny interval), there is a countable set
$T\subset[0,1]$ of the same size as $S$ that is disjoint from $S$. Thus, $\R-T$ is bijective with $\R-S$ by simply swapping elements of $S$ for $T$ and fixing all other reals. But $\R-T$
contains the interval $[2,3]$, and so $\R-S$ is at least as large as $[2,3]$, which has the same size as $\R$. And so $\R-S$ has size continuum.