Note: this is from a paper on Galois Theory, so I believe the technique will come from Galois... Possibly.
I am going to reduce it to the monic case: $x^{21}+a_{20}x^{20}+... a_0$ where all $a_i$ belong to $\{0,1\}$ . I was thinking of trying to generate a polynomial that would satisfy Eisenstein's criterion but it cannot have any prime coefficients.
The easiest starting points are $x^{21}+x$, $x^{21}+x+1$, $x^{21}+x^2$ ...etc
I do not know how to check that these are irreducible without Eisenstein's criterion.. Is it true that since the highest power is odd, if it were irreducible, then it would have a linear factor. So can we just plug in values of $0$ and $1$ until we find a polynomial that gives us a non -zero answer?
So for example, can we say that $f(x)=x^{21}+x+1$ is irreducible, since $f(0)=f(1)=1 \neq 0$?
Is it possible to use Galois Theory to answer these questions?