The following assumes that ZFC is consistent.
As mentioned in the comments, there are a number of remarkable theorems that show that $\mathfrak{c}$ can take on a huge swath of cardinal values and still be consistent with $ZFC$.
There are a number of axioms that do put real restrictions on the size of $\mathfrak{c}$, but they're not (almost) universally used the way that $ZFC$ is.
I also feel that it is an under appreciated fact that in specifying a particular collection of objects that satisfy the axioms of set theory, you actually decide what aleph number $\mathfrak{c}$ is, along with every other question that's independent of $ZFC$ for the model in question. These constructions are called models, and $ZFC$ has many different models that have different properties. For example, there are models in which $\mathfrak{c}=\aleph_{111}$ and models in which it is $\aleph_1$. For any statement, $S$, if $S$ is consistent with $ZFC$ then there is a model of $ZFC$ in which $S$ is true.
Most of mathematics takes place in the realm where all of these different models agree. This is precisely the realm of questions that can be proven true or false with $ZFC$. However, it's not uncommon for questions to crop up that don't fall within this realm. Most mathematicians are currently happy to say that that's a question that doesn't have an answer, though others are pushing for the acceptance of more axioms. Accepting more axioms (notably large cardinal axioms) rules out any model on which those axioms fail to hold as places where you can do "the right kind of mathematics" (there is mathematics done in models that don't conform to $ZFC$ but it's a very very niche field) and so increases the set on which all "acceptable" models (meaning ones that agree with our axioms) agree.
We can ask the philosophical question "is there one true model of $ZFC$ that we should be using," but I think most mathematicians (and definitely most philosophers of science) would say no.
But yes, it is a factual statement to say "a particular construction of the set theoretic universe answers the question of the size of $\mathfrak{c}$" and it is a factual statement to say "the size of $\mathfrak{c}$ is not settled by a set of axioms accepted by the majority of the mathematics community" as most people are agnostic on these stronger axioms I have mentioned. Prof Stewart's statement seems like an immediate corollary of these two assertions.