The question is about a sequence of polynomials in $\,x\,$ whose
generating function is
$$ \sum_{n \geq 0}u_nz^n := \sum_{n \geq 0}u_n(x)z^n =
\frac{1+z}{1+z+x^2 z^2+z^3+z^4}. \tag1 $$
This immediately implies that the sequence satisfies a linear recurrence
with coefficients that are polynomials in $\,x.\,$ It is easy to verify using only the linear recurrence the following results for all integer
$\,n\,$ where $\,y := x^2-1\,$
\begin{align*}
u_{n+4} &= -u_n - u_{n+1} - x^2u_{n+2} - u_{n+3}, \\
u_{n+5} &= u_n +y\,u_{n+2} -y\,u_{n+3}, \\
u_{n+6} &= y\,u_n + x^2u_{n+1} +x^2y\,u_{n+2} + 2y\,u_{n+3}, \\
u_{n+7} &= -2y\,u_n -y\,u_{n+1} +x^2(3-2x^2)u_{n+2} +y(y-1)u_{n+3}.
\tag2 \end{align*}
Define the sequence of polynomials
$$ g_n := (u_n u_{n+6} -u_{n+3} ^2) -
x^2(u_{n+1} u_{n+5} - u_{n+3} ^2). \tag3 $$
Use the results in equation $(2)$ to verify that
$$ g_{n+1} = g_n =
(u_n+u_{n+3})^2 + x^2(u_{n+1}u_{n+3} - u_{n+1}u_{n+2} + u_nu_{n+2}). \tag4 $$
Use induction to conclude that $\,g_n = g_0 := y\,I_1\,$
for all integer $\,n.\,$
From equation $(1)$ the first few values of the $\,u\,$ sequence are
$$ u_{-1} = 0,\;\; u_0 = 1,\;\; u_1 = 0,\;\; u_2 = -x^2,\;\;
u_3 = x^2-1. \tag5 $$
Verify that $\,g_0 = I_1 = 0\,$ for these initial values of $\,u.\,$
This proves the first conjecture
$$ u_n(x)u_{n+6}(x)-u_{n+3}(x)^2 =
x^2(u_{n+1}(x)u_{n+5}(x) - u_{n+3}(x)^2). \tag6 $$
Define the sequence
$$ f_n := (u_{n+1} + u_{n+2})^2 + y\,u_{n+1}u_{n+2} + u_nu_{n+1}
+(u_{n+2}-u_n)u_{n+3}. \tag7 $$
Similar to equation $(4)$ verify that $\,f_{n+1} = f_n\,$ and conclude
that $\,f_n = f_0 := I_2\,$ for all integer $\,n.\,$ Verify that
$\,f_0=I_2=1\,$ For the initial values of $\,u\,$ in equation $(5)$.
Verify the general recurrence result
\begin{align*} I_1u_{n+4}u_{n-4}=\; &
(2I_1+x^2I_2)u_{n+3}u_{n-3} +
((y^2-2)I_1 - x^4I_2)u_{n+2}u_{n-2} +\\
& (1-y)I_1u_{n+1}u_{n-1} +
y((1-y)I_1 + x^2I_2)u_nu_n. \tag8
\end{align*}
Verify that equation $(8)$ is equivalent to equation $(6)$ if
$\,I_1=0\,$ and $\,I_2=1\,$ which is implied by equation $(5)$.
Note that so far, all the algebra required can easily be done by hand.
Given any two integers $\,r,s\,$ define the sequence
$$ h_n := u_n u_{n+r+s} -u_{n+r} u_{n+s} . \tag9 $$
It is conjectured that the sequence $\,h_n\,$ satisfies the recursion
$$ h_{n+5}-h_n = y(h_{n+4} + h_{n+3} - h_{n+2} - h_{n+1}). \tag{10} $$
This is surprisingly simple to prove in great generality.
Suppose that for a fixed positive integer $\,m\,$ and constants $\,c_k\,$
the sequence $\,u\,$ satisfies the linear recursion
$$ u_n := \sum_{k=1}^m c_k u_{n-k}. \tag{11} $$
In the general case, where the characteristic polynomial of the recursion
has no repeated roots, there exists constants $\,a_k\,$ and
roots $\,r_k\,$ such that
$$ u_n = \sum_{k=1}^m a_k r_k{}^n. \tag{12} $$
That is, the sequence $\,u\,$ is a linear combination of powers of the
roots $\,r.\,$ Suppose $\,v\,$ and $\,w\,$ are any two sequences with
the same roots. Then their product sequence is a linear combination of powers of the product of two roots. That is, there exists constants
$\,b_{i,j}\,$ which only depend on the roots $\,r_k\,$ such that
$$ h_n:=v_n w_n = \sum_{1\le i\le j\le m} b_{i,j}(r_ir_j)^n. \tag{13} $$
This implies that there exists constants $\,d_k\,$ which depend
on the roots $\,r_k\,$such that there is a linear recursion for $\,h\,$
$$ h_n = \sum_{k=1}^M d_k h_{n-k}. \tag{14} $$
where $\,M\le m(m+1)/2.\,$
Note that this same recursion holds for any linear combination of
products of two sequences with the same recursion in equation $(11)$.
Thus, in particular, the recursion in equation $(14)$ holds for the
sequence in equation $(9)$.
For the particular sequence $\,u_n\,$ defined in equation $(1)$ it
suffices to show that $\,h_n := u_n^2\,$ satisfies the recursion in
equation $(10)$ using the same techniques used to prove the first
conjecture and this implies that the sequence $\,h\,$ in equation
$(9)$ also satisfies the same recursion. Note that the characteristic
polynomial for $\,u\,$ is palindromic which leads to the simple form
of the recursion in equation $(10)$.
This proves the second conjecture.
I used Wolfram Mathematica extensively to study the natural generalization
of the original sequence of polynomials $\,u_n.\,$ Here is a summary of
the results I found.
Define the sequence $\,u_n\,$ by the recursion with constants $\,c_2,c_3$
$$ u_n = -(c_2 u_{n-1} + c_3 u_{n-2} + c_2 u_{n-3} + u_{n-4}). \tag{15} $$
Define the sequence $\,h_n\,$ as in equation $(9)$. Then it satisfies the
recursion
$$ h_{n+5} - h_n = (1-c_3)(h_{n+4} - h_{n+1})
+ (c_2^2-c_3)(h_{n+3} - h_{n+2}) \tag{16} $$
which is the generalization of equation $(10)$
Notice the general Somos-8 sequence identity
$$ v_0 u_{n+4}u_{n-4} = -(v_1 u_{n+3}u_{n-3} + v_2 u_{n+2}u_{n-2} +
v_3 u_{n+1}u_{n-1} + v_4 u_{n}u_{n}) \tag{17} $$
where the constants $\,v_0,v_1,v_2,v_3,v_4\,$ depend on $\,c_2,c_3\,$
and the initial values $\,u_0,u_1,u_2,u_3.\,$ This is the generalization
of equation $(6)$.