When you use Column (or Grid) a previously styled element with explicit font-size setting appears much smaller. Here is an example
cell = Framed[Style[(2*x^(3/2))/3, FontSize -> 14],
FrameMargins -> 10,
FrameStyle -> {AbsoluteThickness[1], LightGray},
RoundingRadius -> 3];
{cell, Column[{cell}]}

I looked through the options of Column, Grid, and GridBox but I couldn't find how I can prevent this when I output an expression with nested columns or grids. And setting the font-size larger, so that it appears to be non-scaled sounds like a bad idea.
Can anyone give me some insight?
Update
With the help of Roman's answer, I could fix my layout. However, there seems to be a bug in Panel which does not respect the settings. Please compare the two usages of Panel without and with a title:
Column[{Item[cell, AllowScriptLevelChange -> False]}]
Panel[Column[{Item[cell, AllowScriptLevelChange -> False]}]]
Panel[Column[{Item[cell, AllowScriptLevelChange -> False]}], "Hello"]
Three different font-sizes. I simply removed the Panel as it was not extremely important.






ScriptSizeMultipliersbut that's not it.ImageSizeMultiplierssounded good but I couldn't make it work.. hmmm. Waiting for Kuba :) – halirutan Jun 16 '18 at 22:23