I don't think it possible to easily tell, but here is how you might approach this. The multipole moments $T_{\ell, m}(t)$ of the energy density $T^{00}(t, \mathbf x)$ of a source can be written on surfaces of constant time in terms of spherical harmonics as follows:
$$
T_{\ell m}(t) = \int d^3x \, Y^*_{\ell, m}(\theta, \phi)r^\ell\,T^{00}(t, \mathbf x)
$$
Notice that if we write the energy density in terms of spherical harmonics;
$$
T^{00}(t,\mathbf x) = \sum_{\ell, m}c_{\ell, m}(t,r)Y_{\ell, m}(\theta, \phi)
$$
then performing the integration in spherical coordinates and using orthogonality of spherical harmonics (I can give details if you want), we find
$$
T_{\ell, m}(t) = \int dr\, r^{\ell+2} c_{\ell, m}(t,r)
$$
Therefore, we see that if certain of the coefficients $c_{\ell, m}$ in the expansion of the density in terms of spherical harmonics vanish, then the corresponding multipole moment vanishes. The monopole moment corresponds to $\ell = 0$, the dipole moment to $\ell = 1$, and the quadrupole moment to $\ell = 2$.
So say, for example, that the energy density has spherical symmetry, namely
$$
T^{00}(t,\mathbf x) = f(t,r), \qquad r = |\mathbf x|
$$
Then its expansion contains no spherical harmonics with $\ell>0$, so all multipole moments other than the monopole moment vanish. In particular, there is no quadrupole.
So the best advice I can give is to look at the pictures of spherical harmonics, and attempt to get some intuition for when certain energy distributions will contain them in their expansions.
I hope that helps! Let me know of any mistakes and/or typos.
Cheers!
*http://en.wikipedia.org/wiki/File:Harmoniki.png
– user12345 Feb 07 '13 at 11:23