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It is known that there exist a number of radioisotopes of elements commonly used in computer systems. Is the decay of these materials known to affect device performance over time, or is its impact so small as to be immeasurable?

This question occurred to me last night as a friend "cleaned the N64 cartridge" by blowing on the contacts. I've also heard that cosmic ray collisions regularly affect satellite computation. There are a number of "material parameters" to computational science we, as developers and computer scientists, rarely consider.

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