To get the same baseline distances even though the font sizes change from line to line, you should
not have blank lines (which are equivalent to \par) between the lines of text -- instead, force line breaks with \newline instructions, and
end the text in question with \<fontsizeinstruction>\par, where \<fontsizeinstruction> could be \Huge, \huge, \LARGE, \normalsize or something else. Instead of \par, you can also provide one or more entirely blank lines
However, if the font size that's in effect for two consecutive lines is very large (say, "\Huge") but the font size at the end of the entire paragraph is very small (say, "\tiny"), TeX will not let the "Huge" characters on one line "merge" with the characters on the next line (which is what would surely happen if the baseline distance were set blindly to what's appropriate for \tiny-sized text). I.e., TeX automatically applies an emergency baseline stretch factor to prevent the glyphs from two lines from colliding with each other. This behavior, by the way, also kicks in when you have an object, such as an elaborate inline math formula, that's too tall or deep and would cause collisions with the stuff in the lines above/below the one with the large math object.
The effects of which font size is in effect at the end of a "paragraph" on the value of the baseline skip are illustrated in the following example:

\documentclass{article}
\usepackage[margin=1in]{geometry}
\begin{document}
\noindent
\Huge
(1) {\Huge\textbf{Dunt venim dolorerosto do odit}}\newline
(2) {\Huge\textbf{ametum vulla conum dolore}}\newline
(3) {\LARGE conulput in vero od el}\newline
(4) {\LARGE Dunt venim dolorerosto do odit}
% font size in effect: \Huge, hence very wide linespacing
\bigskip\noindent
\LARGE
(1) {\Huge\textbf{Dunt venim dolorerosto do odit}}\newline
(2) {\Huge\textbf{ametum vulla conum dolore}}\newline
(3) {\LARGE conulput in vero od el}\newline
(4) {\LARGE Dunt venim dolorerosto do odit}
\par
\bigskip\noindent
\normalsize
(1) {\Huge\textbf{Dunt venim dolorerosto do odit}}\newline
(2) {\Huge\textbf{ametum vulla conum dolore}}\newline
(3) {\LARGE conulput in vero od el}\newline
(4) {\LARGE Dunt venim dolorerosto do odit}
% font size in effect: \normalsize
\end{document}
{\huge ... }instead of\huge{...}– Sigur Jan 09 '14 at 19:28\hugeand\LARGEare switches, and don't take arguments, but should be put in groups:{\huge this is huge text}. The 'linespace' is determined by the value of the\baselineskipactive at the end of the paragraph. If lines numbered '(1)' through '(4)' are real input lines in your.texfile, that probably explains the different 'interline spacing' you're seeing.... – jon Jan 09 '14 at 19:32