The following code does not output the caption correctly, font appears in normal size, and "Figure" is not boldfaced.
\begin{wrapfigure}{r}{0.5\textwidth}
\vspace{-50pt}
\begin{center}
\includegraphics[width=0.48\textwidth]{figure.png}
\end{center}
\caption{bla bla bla}
\vspace{-20pt}
\label{fig4}
\end{wrapfigure}
I use at the beginning
\documentclass{IOS-Book-Article}
\usepackage{times}
\normalfont
\usepackage[T1]{fontenc}
\usepackage{amsmath}
\usepackage{breqn}
\usepackage{graphicx}
\usepackage{float}
\usepackage{caption}
\usepackage{wrapfig}
\usepackage{algorithm}
\usepackage{algorithmic}
l2tabu-en. Thou shall not usecenterin float environments. – Martin Schröder Jul 28 '11 at 21:13