See the MWE below. The tuple falls outside the margin. If I make the sentence a bit shorter or longer then it works fine. So this is unreliable.
Now I can off course force line break before the tuple, but (1) that is not very neat and (2) i am curious how to get this line breaking working dynamically.
It should preferable break after a comma, and then start at the beginning of the line (not at the start of the tuple).
What I tried myself (based on a search here) was using package breqn but not a lot of luck.
Problem screenshot:
Overfull \hbox (97.23221pt too wide) in paragraph at lines 6--7
MWE
\documentclass{article}
\usepackage[english]{babel}
\newtheorem{mydef}{Definition}
\begin{document}
\begin{mydef}
ab long line so that the tupple is at the end of the line $\left \langle w_{asdasd},v_{asdasd},x_{sdasdsad},y_{asdasd}\right \rangle$ bla bla.
\end{mydef}
\end{document}

$\left \langle w_{asdasd}\right.$, $v_{asdasd}$, $x_{sdasdsad}$, $\left.y_{asdasd}\right \rangle$– Aug 17 '15 at 13:19