With TikZ is easy to:
\documentclass[border=3mm,
tikz,
prewiev]{standalone}
\usetikzlibrary{matrix}
\begin{document}
\begin{tikzpicture}
\matrix[matrix of math nodes,
left delimiter=(,
right delimiter=),
nodes in empty cells] (m)
{
0 & 0 & 0 & 0 & \dots & 0 \\
0 & \vphantom{0}
& & & & \\
0 & & & & & \\
0 & & & & & \\
\vdots & & & & & \\
0 & & & & & \\
};
\fill[blue!30] (m-2-2.north west) -| (m-6-6.south east);
\fill[ red!30] (m-2-2.north west) |- (m-6-6.south east);
\draw[line width=3mm,white] (m-2-2.north west) -- (m-6-6.south east);
\draw[thick,stealth-stealth] (m-2-2.north west) -- (m-6-6.south east);
\end{tikzpicture}
\end{document}

Edit:
Gonzalo Medina remind me on the forgotten dots, Sorry for this. Now I add them in the first row and column and also appearance of diagonal line with use white background line.
Edit (2):
The matrix will be centered in text, if you enclose with \begin{center} ... \end{center} or put in some other appropriate environment, for example \begin{figure}\centering\begin{tikzpicture} ... \end{tikzpicture}\end{figure}, etc.
For rounded shadow fill you need to add option rounded corners. Se new MWE below.
\documentclass{article}
\usepackage{tikz}
\usetikzlibrary{matrix}
\usepackage[active,tightpage]{preview}% just for show only picture
\PreviewEnvironment{center}%
\setlength\PreviewBorder{1em}
\begin{document}
\begin{center}
\begin{tikzpicture}
\matrix[matrix of math nodes,
left delimiter=(,
right delimiter=),
nodes in empty cells] (m)
{
0 & 0 & 0 & 0 & \dots & 0 \\
0 & \vphantom{0}
& & & & \\
0 & & & & & \\
0 & & & & & \\
\vdots & & & & & \\
0 & & & & & \\
};
\fill[rounded corners,blue!30] (m-2-2.north west) -| (m-6-6.south east);
\fill[rounded corners, red!30] (m-2-2.north west) |- (m-6-6.south east);
\draw[line width=3mm,white] (m-2-2.north west) -- (m-6-6.south east);
\draw[thick,stealth-stealth] (m-2-2.north west) -- (m-6-6.south east);
\end{tikzpicture}
\end{center}
\end{document}

auto-pst-pdfallows pstricks code to be compiled with pdflatex. Although pdf format is a subset of postcript it lacks a computing engine so pstricks code cannot be used directly with pdflatex. You have to launch pdflatex with the--enable-write18switch if you're under MiKTeX, or--shell-escapewith TeX Live or MacTeX. For XeLaTeX, normally it does not require theauto-pst-pdfpackage for pstricks code. I'll test what happens with XeLaTeX. – Bernard Sep 08 '15 at 18:45auto-pst-pdf, but then you must replace thepostscriptenvironment withpspicture. – Bernard Sep 08 '15 at 18:59eps2pdfthen incorporates the resulting pdf image into the main pdf file. Unfortunately, I don't use TeXshop, but I'm sure you can configure it to add the--shell-escapeswitch to pdflatex. It is not enabled by default for security reasons. – Bernard Sep 08 '15 at 20:04