Here's TeX's line-breaking approach (as I understand it) in a nutshell:
If
\pretoleranceis positive, try to break a paragraph into lines without inserting discretionary hyphens and without exceeding a badness of\pretolerance.If method 1 fails, allow hyphenation and try not to exceed a badness of
\tolerance.If method 2 fails and
\emergencystretchis positive, try again with the amount of "tolerable" white space per text line increased by\emergencystretch.
On p. 96 of the TeXbook, Knuth reports experiments showing that "the first pass [without hyphenation] succeeds more than 90% of the time" for "fairly wide" lines, but fails quickly for "very narrow" ones. He also states that the first pass is done "[i]n order to save time". My interpretation of this is as follows:
For cases where line-breaking without hyphenation fails, one would in fact save time by omitting the first pass (i.e., setting
\pretolerance=-1).It is also possible (though maybe not very likely for languages with a small average word length) that the first pass will succeed, but that allowing hyphenation would have resulted in a solution with smaller badness.
As Knuth nevertheless chose a default value of
100for\pretolerance, he must have regarded the net time savings from "trying without hyphenation" as worthwile, given the average processing power of the time when he adopted these settings.
I don't know if the default settings for TeX's line-breaking algorithm changed over time. But isn't it possible that formerly substantial net time savings are irrelevant today?
So: Is it still worthwhile to let TeX try line-breaking without hyphenation? Or is it preferable by now to adopt \pretolerance=-1 as default setting?

\hyphenpenaltymight be a solution, but I think that the "first pass" takes comparatively short time. Probably @Taco knows better. – egreg Sep 25 '11 at 19:48