Mathematics in PDFs can be cumbersome for any purpose but reading or printing. In particular, copying mathematics in order to use it in another document, and screen-reading for visually impaired consumers.
Both issues can be solved using the accsup package; see
- here for copy-pasting (use
accsupto add detokenized math environment) and - here for screen-reading (use
accsupto add a natural language version).
Since both solutions use the same mechanism, it is not clear how to achieve both at the same time, or if that is even possible.
Can we annotate formulae in PDFs so that they can be copy-pasted nicely and read by screen-reading software?

unicode-math, can be copied and pasted pretty well. – Sergei Golovan Feb 08 '17 at 07:48accsupto annotate formulae with their MathML equivalent? That would not really solve bullet one (but solve another problem, I guess), and I don't know if it solves bullet two. Do screen readers deal well with MathML? – Raphael Feb 08 '17 at 07:56<img>tags don't have analtattribute. (Of course, nobody can check that the content is reasonable...) – Raphael Feb 08 '17 at 14:25