If it absolutely has to be Times New Roman, as opposed to some Times Roman clone, you'll have to use either LuaLaTeX or XeLaTeX. Most (virtually all?) operating systems feature Times New Roman as a system font, and both LuaLaTeX and XeLaTeX provide access to system fonts. As pdfLaTeX doesn't offer direct access to system fonts, you'll have to make do with a (high-quality!) clone of Times Roman if you work with pdfLaTeX.
The code shown at the bottom of this answer should get you started with both LuaLaTeX and pdfLaTeX.
Here's the output produced by LuaLaTeX (MacTeX 2017, MacOSX 10.13.2 "High Sierra"):

And here's the output produced by pdfLaTeX on the same system.

I'd say that only real font experts will readily detect differences between Times New Roman (shown in the upper screenshot) and Times Roman (shown in the lower screenshot.
\documentclass[a4paper,11pt]{article}
\usepackage{graphicx,multirow}
\usepackage{amssymb,amsmath,amsthm}
\usepackage{lscape,lipsum,microtype}
\usepackage[margin=2.5cm]{geometry} % choose page parameters suitably
\usepackage{hyperref}
\usepackage{ifluatex}
\ifluatex
\usepackage{unicode-math}
\setmainfont{Times New Roman}
\setmathfont{Stix Two Math}[Scale=MatchLowercase]
\else % assume pdfLaTeX
\usepackage[utf8]{inputenc}
\usepackage[T1]{fontenc}
\usepackage{newtxtext,newtxmath} % Times Roman clone
\fi
\linespread{1.17647} % = 16/13.6. Why 13.6? Because
%% 13.6 is the "standard" value of baselineskip
%% for Times Roman set at 11 pt.
\begin{document}
\lipsum[2]
\em\lipsum[2]
\end{document}
amssymbpackage, there's really no need, or justification, for loading the deprecatedlatexsympackage. And, thehyperrefpackage should be loaded last, not first. – Mico Dec 19 '17 at 21:49fontspecpackage for that and the font installed on your machine. There should be plenty resources about using a system font in LaTeX. – Skillmon Dec 19 '17 at 21:59epsfig! – Ian Thompson Dec 19 '17 at 22:16epsfigIf the OP’s TeX distribution is less than ca 12 years old? :-) – Mico Dec 19 '17 at 22:32