In the table above, the three columns below the multicolumn are smaller and are aligned to the left. However, I want them to be vertically centered with respect to the largest multicolumn above them as follows
\documentclass{book}
\usepackage[x11names]{xcolor}
\usepackage[a4paper]{geometry}
\geometry{twoside=true, showframe=false}
% Horizontal
\geometry{inner=5mm, outer=5mm, includemp=true, bindingoffset=5mm, marginparsep=3.5mm, marginparwidth=15mm}
% Vertical
\geometry{top=20mm, vmarginratio=3:5, includehead=true, includefoot=true, headheight=8pt, headsep=14pt, footskip=5mm}
\usepackage{ragged2e}
\usepackage{tabularx}
\newcolumntype{C}{ >{\arraybackslash \Centering}X }
\usepackage{booktabs}
\usepackage{makecell}
\usepackage{mathtools}
\begin{document}
\begin{table*}[htb]
% Center the table
\centering
\begin{tabularx}{\textwidth}{*{3}{l} >{\hsize=0.75\hsize}C !{\vrule width 0.25mm}*{3}{l} >{\hsize=0.75\hsize}C !{\vrule width 0.25mm}>{\hsize=1.5\hsize}C}
\toprule
\multicolumn{3}{c}{Exhaustive Search Method} & & \multicolumn{3}{c}{Proposed Method} & &
\\
\Xhline{0.25mm}
\multicolumn{3}{c}{Combination of POIs} & $\mathit{SDSCR_{min}}$ & \multicolumn{3}{c}{Combination of POIs} & $\mathit{SDSCR_{min}}$ & Reference POIs
\\
\Xhline{0.25mm}
33 & 36 & 35 & 4.90 & 33 & 36 & 35 & 4.90 & 36
\\
34 & 33 & 35 & 5.23 & 34 & 33 & 35 & 5.23 & 34
\\
11 & 5 & 31 & 5.63 & 11 & 5 & 31 & 5.63 & 11
\\
33 & 14 & 35 & 5.73 & 33 & 14 & 35 & 5.73 & 31
\\
14 & 5 & 31 & 5.76 & 14 & 5 & 31 & 5.76 & 14
\\
\Xhline{0.25mm}
\multicolumn{3}{c}{\color{DodgerBlue2} \bfseries Time 8.8 s} & & \multicolumn{3}{c}{\color{DodgerBlue2} \bfseries Time 0.46 s} & &
\\
\bottomrule
\end{tabularx}
\end{table*}
\end{document}




