The default vertical spacing within an align environment seems very tight when there are fractions in the lines.

I am aware of three manual tweaks that can be applied:
- Adjust the value
\jot. - Add a vertical space on each line where necessary via
\\[<amount>]. - Use the
spreadlinesenvironment from the mathtools package.

Solutions 1 and 3 add vertical space even between the lines that don't need them, so if the set of equations has lines without fractions (and lines with fractions), the spacing is not quite right.
Question:
Is there not some automated solution to always leave the appropriate vertical space between the bottom of one line and the top of the next?
References:
- Length parameter for vertical skip space in a math environment?
- How to make formulae take equal vertical space in the align environment?
Code:
\documentclass{article}
\usepackage{mathtools}% includes amsmath
\begin{document}
\begin{minipage}[t]{0.20\linewidth}
\textbf{Nice}
\begin{align}
x &= 73 \times 2\
&= 146
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.25\linewidth}
\textbf{Not so nice}
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
\bigskip\par\noindent
\textbf{Manual Tweak Options:}
\medskip\par\noindent
\begin{minipage}[t]{0.25\linewidth}
\textbf{Tweak jot}
\setlength{\jot}{8pt}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\textbf{Add vertical space}
\begin{align}
x &= \frac{146}{10}\[5pt]% tweak
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\textbf{spreadlines}
\begin{spreadlines}{0.8em}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{spreadlines}
\end{minipage}%
\end{document}
Testing Proposed fix:
I tested the proposed fix, and it does seem to fix the "Not so nice" section:

Not sure I like the additional vertical space at the top.
But furthermore, it also adds spacing where it is not needed as was the case in the section that was previously "Nice":

In cases where there are manual adjustments, they should probably not be extended (or only extended if the spacing is not sufficient. Personally I can work without this, but perhaps a method of disabling it would be good:

Code:
\documentclass{article}
\usepackage{mathtools}% includes amsmath
\begin{document}
\par\noindent
%---------------------------------------- Oringally "Nice"
\begin{minipage}[t]{0.30\linewidth}
\textbf{Nice}
\begin{align}
x &= 73 \times 2\
&= 146
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\makeatletter
\def\align@preamble{%
&\hfil
\setboxz@h{@lign$\m@th\displaystyle{##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\tabskip\z@skip
&\setboxz@h{@lign$\m@th\displaystyle{{}##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\hfil
\tabskip\alignsep@
}%
\makeatother
%
%
\textbf{With 2012-05-09 fix:}
\begin{align}
x &= 73 \times 2\
&= 146
\end{align}
\end{minipage}%
\bigskip\par\noindent
%---------------------------------------- Oringally "Not so Nice"
\begin{minipage}[t]{0.30\linewidth}
\textbf{Not so nice}
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\makeatletter
\def\align@preamble{%
&\hfil
\setboxz@h{@lign$\m@th\displaystyle{##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\tabskip\z@skip
&\setboxz@h{@lign$\m@th\displaystyle{{}##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\hfil
\tabskip\alignsep@
}%
\makeatother
%
\textbf{With 2012-05-09 fix:}
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
\bigskip\par\noindent
\textbf{Manual Tweak Options:}
\medskip\par\noindent
%---------------------------------------- Adjust \jot
\begin{minipage}[t]{0.30\linewidth}
\textbf{Tweak jot}
\setlength{\jot}{8pt}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\makeatletter
\def\align@preamble{%
&\hfil
\setboxz@h{@lign$\m@th\displaystyle{##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\tabskip\z@skip
&\setboxz@h{@lign$\m@th\displaystyle{{}##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\hfil
\tabskip\alignsep@
}%
\makeatother
%
\textbf{With 2012-05-09 fix:}
\setlength{\jot}{8pt}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
%---------------------------------------- Adding Vertical Space
\bigskip\par\noindent
\begin{minipage}[t]{0.30\linewidth}
\textbf{Add vertical space}
\begin{align}
x &= \frac{146}{10}\[5pt]% tweak
&= \frac{73}{5}
\end{align}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\makeatletter
\def\align@preamble{%
&\hfil
\setboxz@h{@lign$\m@th\displaystyle{##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\tabskip\z@skip
&\setboxz@h{@lign$\m@th\displaystyle{{}##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\hfil
\tabskip\alignsep@
}%
\makeatother
%
\textbf{With 2012-05-09 fix:}
\begin{align}
x &= \frac{146}{10}\[5pt]% tweak
&= \frac{73}{5}
\end{align}
\end{minipage}%
%---------------------------------------- Spreadlines
\bigskip\par\noindent
\begin{minipage}[t]{0.30\linewidth}
\textbf{spreadlines}
\begin{spreadlines}{0.8em}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{spreadlines}
\end{minipage}%
%
\begin{minipage}[t]{0.30\linewidth}
\makeatletter
\def\align@preamble{%
&\hfil
\setboxz@h{@lign$\m@th\displaystyle{##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\tabskip\z@skip
&\setboxz@h{@lign$\m@th\displaystyle{{}##}$}%
\ifdim\ht\z@<\ht\strutbox@
\ht\z@\ht\strutbox@
\dimen@\ht\strutbox@
\advance\dimen@.15em
\ht\strutbox@\dimen@
\fi
\strut@
\ifmeasuring@\savefieldlength@\fi
\set@field
\hfil
\tabskip\alignsep@
}%
\makeatother
%
\textbf{With 2012-05-09 fix:}
\begin{spreadlines}{0.8em}% tweak
\begin{align}
x &= \frac{146}{10}\
&= \frac{73}{5}
\end{align}
\end{spreadlines}
\end{minipage}%
\end{document}

alignthe distance between the lines (the equals signs, to give an indication) should generally be constant. Fine tuning math alignments can be done only looking at them and knowing the meaning of the formulas. – egreg May 06 '12 at 08:36$\setlength{\jot}{8pt}$. I am just trying to do this for the posts that I put on SE - as with http://math.stackexchange.com/questions/988865/optimization-problem-rowing-across-a-lake/988866#988866. – ahorn Oct 24 '14 at 09:43\documentclassand the appropriate packages that reproduces the problem and post a new question on TeX.SE. – Peter Grill Oct 24 '14 at 17:31cellspacepackage does a similar job for tabular/arrays. It defines a minimal vertical spacing at the top and bottom of cells in a column. – Bernard Aug 06 '15 at 14:47