Something like this?
The \mkern2mu directive inside the argument of \mathllap serves to places the \times symbol right below the gap between the two horizontal braces. (A larger value for the argument of \mathllap would push the \times symbol further to the left.) Likewise, \mathrlap{\cramped{\,=\,2^{12}}} serves to place =2^{12} to the right of the main argument of the second \underbrace directive.

\documentclass{article}
\usepackage{mathtools} % for '\mathllap', '\mathrlap', and '\cramped' macros
\begin{document}
[
\underbrace{4}_{2^2}
\underbrace{\mathrm{KB}}%
_{\mathllap{\times\mkern2mu}
2^{10} % <-- main argument of '\underbrace'
\mathrlap{\cramped{,=,2^{12}}}}
]
\end{document}