I have no idea why you would do this using a description environment and not an enumerate (as in the other answer), but who am I to question? :)
In the code below, I've borrowed some ideas from Enumerated description list and have introduced a couple of new counters descriptcounti and descriptcountii; if you plan to have deeper lists, just keep going (descriptcountiii, etc)

\documentclass{article}
\usepackage{enumitem}
% first level
\newcounter{descriptcounti}
\setlist[description]{%
before={\setcounter{descriptcounti}{0}},%
,font=\bfseries\refstepcounter{descriptcounti}\thesubsection.\thedescriptcounti~}
% second level
\newcounter{descriptcountii}
\setlist[description,2]{%
before={\setcounter{descriptcountii}{0}},%
,font=\bfseries\refstepcounter{descriptcountii}\thesubsection.\thedescriptcounti.\thedescriptcountii~}
\begin{document}
\setcounter{section}{4} % just for demonstration
\subsection{Sub section}
\begin{description}
\item item one
\item item two
\item item three
\begin{description}
\item item one
\item item two
\item item three
\end{description}
\end{description}
\end{document}
Following the comments, you can easily apply this to a custom description, say mydesc, by using \newlist
\documentclass{article}
\usepackage{enumitem}
\newlist{mydesc}{description}{5}
% first level
\newcounter{descriptcounti}
\setlist[mydesc]{%
before={\setcounter{descriptcounti}{0}},%
,font=\bfseries\refstepcounter{descriptcounti}\thesubsection.\thedescriptcounti~}
% second level
\newcounter{descriptcountii}
\setlist[mydesc,2]{%
before={\setcounter{descriptcountii}{0}},%
,font=\bfseries\refstepcounter{descriptcountii}\thesubsection.\thedescriptcounti.\thedescriptcountii~}
\begin{document}
\setcounter{section}{4} % just for demonstration
\subsection{Sub section}
\begin{mydesc}
\item item one
\item item two
\item item three
\begin{mydesc}
\item item one
\item item two
\item item three
\end{mydesc}
\end{mydesc}
\end{document}