beamerbaseoverlay.sty contains
\newcommand<>{\emph}[1]{{\only#2{\itshape}#1}}
so \emph only produces italic shape. However, \em is not changed and you can write
\documentclass{beamer}
\begin{document}
\frame{\em abc {\em def {\em ghi} jkl} mno}
\end{document}
giving

which produces the shapes you expect, but is not overloaded with the overlay options beamer provides in its modified \emph. The overlay options mean that you can write \emph<3>{text} to print the text on all slides but italise it only on slide 3. If you are willing to forego this functionality and just want \emph to behave like {\em ...} then you can put
\renewcommand<>{\emph}[1]{{\em #1}}
in your preamble. Added: As you comment, the above may be combined to get the overlay behaviour via:
\renewcommand<>{\emph}[1]{{\only#2{\em}#1}}
As other posters note, often one would prefer to use beamer commands such as \alert for extra contrast in presentations.
beamer, I guess here as it likely use cases are pretty rare. – Joseph Wright Jan 05 '13 at 09:47beamerdefines the command\alert. About your problem, nesting emph commands should be used to over-emphasize a part of text, not to make the text back to its default level of emphasization, so defining a second emphasize command for that purpose would be a solution. In case what you want is simply to come back to the default level, the natural way of doing so is to close the macro and open a second one. – T. Verron Jan 05 '13 at 10:00\emand\emph. It is just for nested\emphs. – Guido Jan 05 '13 at 10:02\emphs. – Jan 05 '13 at 10:49beameris widely-used and I don't want to break things for users. (Also, it's not clear whether this was a deliberate decision or an oversight!) – Joseph Wright Jan 05 '13 at 12:56\emin a presentation, yet, that's my choice :) Besides, the initial problem is that I am quoting an author who is using emphasis in his text, and that does not deserve\alerteither. Both{quote}and\emphwhere not behaving properly (accordingly to my expectations, agreed), I fixed the first one, but missed the second. Thanks to all! – akim Jan 06 '13 at 11:12