I tried to do this in tikz, the code is quite long but well...
I managed to do everything except those irregular sine paths. I'm afraid I'm not at that level yet. If I find I solution I'll let you know but I'm not sure.
Please note that there might be better solutions than this one, and if you need to do this multiple times, it would be better for you to look for ways to automatize a lot of the options in some way.

\documentclass[border=1cm]{standalone}
\usepackage[T1]{fontenc}
\usepackage{tikz}
\usetikzlibrary{positioning, calc, decorations, decorations.pathmorphing, shapes.arrows, snakes}
\definecolor{outerblue}{RGB}{50,100,170}
\definecolor{innerblue}{RGB}{70,110,170}
\definecolor{lightblue}{RGB}{155,210,220}
\tikzset{sqr/.style={draw=outerblue, thick,rectangle,fill=white,minimum size=1cm},
cir/.style={draw=outerblue, thick,circle,fill=white,minimum size=1cm},
every label/.style={font=\tiny, text width=2cm},
liltext/.style={font=\tiny, inner sep=.5mm},
bigarrow/.style={single arrow,
single arrow head extend=.2mm,
draw=outerblue,
fill=innerblue,
line width=1pt,
shorten >= 4.5pt,
minimum size=4mm,
text width=4mm,
inner sep=.1mm},
doublea/.style={thick, fill=none, double, double distance=1.5pt},
}
\newcommand{\dil}[1]{\draw[very thick] ($(#1.south west)+(-2mm, -2mm)$) -- ($(#1.north east)+(2mm, 2mm)$);}
\begin{document}
\begin{tikzpicture}
% SHAPES
\node (sqr1) [sqr, label={[align=right,anchor=south east]left:Daniel\\\color{red}?\\"foi-se abaixo depois da morte da minhã mãe"}] {}; \dil{sqr1}
\node (sqr2) [sqr, right=8mm of sqr1, label={[anchor=south west]right:João\\\color{red}?\\Pneumonia}] {}; \dil{sqr2}
\node (cir1) [cir, right=1.5cm of sqr2, label={[anchor=south west]right:Maria José\\\color{red}62\\"coração"}] {}; \dil{cir1}
\node (sqr3) [sqr, right=2cm of cir1, label={[anchor=south west]right:Jorge\\\color{red}?\\AVG}] {}; \dil{sqr3}
\node (cir2) [cir, right=1cm of sqr3, label={[anchor=south west]right:Teresa\\\color{red}?\\"causa natural"}] {}; \dil{cir2}
\node (cir3) [cir, below=1.5cm of sqr1, xshift=5mm, label={[align=right, anchor=south east]left:Fernanda\\65\\AVC (2011)}] {};
\node (sqr4) [sqr, right=2.3cm of cir3, label={[align=right, anchor=south east]left:António\\75\\HTA, DM, asma, HBP}] {};
\node (sqr5) [sqr, right=1cm of sqr4, yshift=8mm, label={[yshift=4mm,align=right, anchor=south east]left:?}] {}; \dil{sqr5}
\node (cir4) [cir, below=1.5cm of sqr3, xshift=1cm, label={[anchor=south west]right:Gilda\\71\\Dislipidémia AVC (2005)}] {};
\node (sqr6) [sqr, below=1.5cm of cir3, label={[align=right,anchor=south east]left:Armando\\?}] {};
\node (cir5) [cir, below=1.5cm of sqr4, xshift=-5mm, label={[anchor=south west]right:Cristina\\45}] {};
\node (sqr7) [sqr, right=2.5cm of cir5, label={[yshift=4mm,align=right,anchor=south east]left:?}] {};
\node (cir6) [cir, below=1.5cm of cir4, xshift=5mm, label={[anchor=south west]right:Angela\\43}] {};
\node (sqr8) [sqr, below=1.5cm of sqr6, xshift=-2mm, label={[align=right,anchor=south east]left:Igor\\16}] {};
\node (sqr9) [sqr, below=1.5cm of cir5, xshift=2mm, label={[anchor=south west]right:Leandro\\12}] {};
\node (sqr10)[sqr, below=1.5cm of sqr7, xshift=1cm, label={[anchor=south west]right:Bruno Rafaeli\\20}] {};
% LINES
\draw[doublea, draw=lightblue] (sqr1.south) -- (sqr4.north);
\draw[doublea, draw=lightblue] (sqr2.south) -- (sqr4.north);
\draw[doublea, draw=lightblue] (cir1.south) -- (sqr4.north);
\draw[doublea, draw=lightblue] (sqr4.east) -- (cir4.west);
\draw[doublea, draw=lightblue] (sqr4.south) -- (cir5.north);
\draw[thick, draw=lightblue] (cir4.south) -- (cir6.north);
\draw (sqr1) |- ([xshift=0em,yshift=-5mm]sqr1.south) -| (cir1.south);
\draw (sqr2) |- ([xshift=0em,yshift=-3mm]sqr2.south) -| (cir1.south);
%\draw (sqr3.south) |- to node[near start,above](center1){H} -| (cir2.south);
\draw (sqr3) |- ([xshift=0em,yshift=-4mm]sqr3.south) -| (cir2.south);
\draw (cir4) -- ($(sqr3.south)!0.5!(cir2.south)+(0mm,-4mm)$);
\draw (cir3) |- ([xshift=0em,yshift=4mm]cir3.north) -| (sqr4.north);
\draw[decoration={snake}, decorate] ($(cir3.north)!0.5!(sqr4.north)+(0mm,4mm)$) -- ($(sqr2.south)!0.5!(cir1.south)+(0mm,-3mm)$);
\draw (sqr5) |- ([xshift=0em,yshift=-1cm]sqr5.south) -| (cir4.south);
\draw (sqr4) |- ([xshift=0em,yshift=-6mm]sqr4.south) -| (cir4.south);
\draw ($(sqr4.south)!0.5!(cir4.south)+(0mm,-6mm)$) node[liltext, above]{1966} -- ($(cir5.north)!0.5!(cir6.north)+(0mm,6mm)$);
\draw (cir5) |- ([xshift=0em,yshift=6mm]cir5.north) -| (cir6.north);
\draw (sqr6) |- ([xshift=0em,yshift=-3mm]sqr6.south) -| (cir5.south);
\draw ($(sqr6.south)!0.5!(cir5.south)+(0mm,-3mm)$) node[liltext, above]{1995} -- ($(sqr8.north)!0.5!(sqr9.north)+(0mm,3mm)$);
\draw (sqr8) |- ([xshift=0em,yshift=3mm]sqr8.north) -| (sqr9.north);
\draw (sqr7) |- ([xshift=0em,yshift=-3mm]sqr7.south) -| (cir6.south);
\draw (sqr10) -- ($(sqr7.south)!0.5!(cir6.south)+(0mm,-3mm)$) node[liltext, above, anchor=south east]{1999};
\draw[doublea] ($(sqr7.south)!0.5!(cir6.south)+(-2mm,-5mm)$) -- ($(sqr7.south)!0.5!(cir6.south)+(2mm,-1mm)$);
\node[bigarrow, anchor=east, rotate=225] at ($(sqr4.north east)+(.5mm,.5mm)$) {};
\draw [red!60!black, dashed, thick] plot [smooth cycle] coordinates {
([yshift=2mm]sqr4.north east)
([yshift=-3mm]sqr5.south west)
([yshift=-3mm]sqr5.south east)
([yshift=2mm]cir4.north west)
([yshift=1.7mm]cir4.north east)
([xshift=1.2mm]cir4.east)
([yshift=-3mm]cir4.south)
([xshift=-1.8mm,yshift=-2.3mm]sqr4.south)
%([xshift=-1mm]sqr4.west)
([yshift=1mm]sqr4.north west)
};
\end{tikzpicture}
\end{document}
tikzin so short time. – Sigur Oct 28 '13 at 20:28matrixlibrary fromtikzseems to ease things up. Besides this, I'm surprised that medical students also use Latex. I thought its users are rather from math/physics. – Jost Oct 29 '13 at 17:43