The CSV reading capabilities of pgfplots lack escaping support. Consequently, the short answer is: there no way to (un)escape arbitrary CSV columns for pgfplots, sorry.
There is also no builtin support to plot datetimes at the required precision (your data files live on a scale of deciseconds or milliseconds).
You comment indicates that you are searching for a fully fledged and robust solution which simply works in all case. In this case you may need to evaluate a different tool.
That said, there are ways to get the plot that you asked for. This stretches the limits of pgfplots beyond its builtin capabilities, and is not stable for all input types, so beware.
Regarding the question how to read the data files: pgfplots comes with support to silently ignore characters from the input files. In your case, that would suffice to read the files. The way to go would be something like
\addplot table [x=clock, y=created_at, col sep=comma, ignore chars={\#,\"}] {./processor.csv};
in which case any occurrence of either " or # would silently be stripped away. This really reads all records of the attached file.
Fortunately, this data file contains no , characters inside of the string columns (which is pure luck, of course - it would fail as soon as a data set contains a comma).
There is another limitation of pgfplots, as mentioned above: your data files use datetimes on one of the axes, and the provided data file lives on a scale of tens of seconds. Pgfplots, however, has to use the limited arithmetics offered by TeX (max 32 bit integers) and supports at most datetime ranges with minute scales.
While this could be tweaked using suitable transformations (as in pgfplots data time format), it is not an "out-of-the-box" solution. Here is a suggested adoption which supports times (but ignores the date part). It is adopted from the answer of @Jake mentioned above:
\documentclass{standalone}
\usepackage{pgfplots}
\pgfplotsset{compat=1.12}
\usepgfplotslibrary{dateplot}
% this strips the date (silently!) and considers only the time
\def\transformtime#1 #2:#3:#4.#5!{
\pgfkeys{/pgf/fpu=true,/pgf/fpu/output format=fixed}%
\count2=#2 \edef\hour{\the\count2}%
\count2=#3 \edef\min{\the\count2}%
\count2=#4 \edef\sec{\the\count2}%
\pgfmathparse{\hour*3600-\pgfkeysvalueof{/pgfplots/timeplot zero}*3600+\min*60+\sec + 0.#5}%
\pgfkeys{/pgf/fpu=false}%
%\message{got #1 #2:#3:#4.#5 -> \pgfmathresult^^J}%
}
\pgfplotsset{
timeplot zero/.initial=0,
timeplot/.style={
y coord trafo/.code={\expandafter\transformtime##1!},
y coord inv trafo/.code={%
\pgfkeys{/pgf/fpu=true,/pgf/fpu/output format=fixed}
\pgfmathsetmacro\hours{floor(##1/3600)+\pgfkeysvalueof{/pgfplots/timeplot zero}}
\pgfmathsetmacro\minutes{floor((##1-(\hours-\pgfkeysvalueof{/pgfplots/timeplot zero})*3600)/60)}
\pgfmathsetmacro\seconds{##1-floor(##1/60)*60}
\def\pgfmathresult{\pgfmathprintnumber{\hours}:\pgfmathprintnumber{\minutes}:\pgfmathprintnumber[fixed zerofill]{\seconds}}
\pgfkeys{/pgf/fpu=false}
},
scaled y ticks=false,
yticklabel=\tick,
}
}
\begin{document}
\begin{tikzpicture}
\begin{axis}[
xmax=1000,
timeplot,
]
\addplot+[only marks]
table [x=clock, y=created_at, col sep=comma, ignore chars={\#,\"}] {./processor.csv};
\end{axis}
\end{tikzpicture}
\end{document}

LIMITATIONS:
- an escaped comma in the CSV file will break the parsing routine
- data points must be on one day, no sanity check in this macro
- your data file contains a couple of data points without x coordinate, these are dropped
The data file used to reproduce this set is
id,created_at,updated_at,manufacturer_id,processor_family_id,microarchitecture_id,code_name_id,technology_id,cache_on_id,cache_off_id,die_photo_id,model,date,clock,max_clock,hw_nthreadspercore,hw_ncores,tdp,source,bus_width,transistors,die_size,vdd_low,vdd_high
1,"2014-11-17 00:01:26.708453","2014-11-17 00:01:26.708453",9,1,,1,,1,2,,3.60E,,3600,,1,1,110,http://ark.intel.com/products/27089/64-bit-Intel-Xeon-Processor-3_60E-GHz-2M-Cache-800-MHz-FSB,,169,135,1.2875,1.3875
2,"2014-11-17 00:01:26.732099","2014-11-17 00:01:26.732099",9,1,,1,,1,2,,3.6,,3600,,2,1,110,http://ark.intel.com/products/28019/64-bit-Intel-Xeon-Processor-3_60-GHz-2M-Cache-800-MHz-FSB,,169,135,1.25,1.388
3,"2014-11-17 00:01:26.754340","2014-11-17 00:01:26.754340",9,1,,1,,1,2,,3.80E,,3800,,1,1,110,http://ark.intel.com/products/27092/64-bit-Intel-Xeon-Processor-3_80E-GHz-2M-Cache-800-MHz-FSB,,169,135,1.2875,1.3875
4,"2014-11-17 00:01:26.796928","2014-11-17 00:01:26.796928",9,1,,2,,3,2,,,,3660,,2,1,110,http://ark.intel.com/products/27103/64-bit-Intel-Xeon-Processor-3_66-GHz-1M-Cache-667-MHz-FSB,,125,112,1.2875,1.4
5,"2014-11-17 00:01:26.847382","2014-11-17 00:01:26.847382",9,2,,3,,4,2,,310,,2130,,1,1,73,http://ark.intel.com/products/27104/Intel-Celeron-D-Processor-310-(256K-Cache-2_13-GHz-533-MHz-FSB),,125,112,1.25,1.4
6,"2014-11-17 00:01:26.868530","2014-11-17 00:01:26.868530",9,2,,3,,4,2,,315,,2260,,1,1,73,http://ark.intel.com/products/27105/Intel-Celeron-D-Processor-315-(256K-Cache-2_26-GHz-533-MHz-FSB),,125,112,1.25,1.4
7,"2014-11-17 00:01:26.888672","2014-11-17 00:01:26.888672",9,2,,3,,4,2,,315J,,2260,,1,1,73,http://ark.intel.com/products/27106/Intel-Celeron-D-Processor-315315J-(256K-Cache-2_26-GHz-533-MHz-FSB),,125,112,1.25,1.4
8,"2014-11-17 00:01:26.908313","2014-11-17 00:01:26.908313",9,2,,3,,4,2,,320,,2400,,1,1,73,http://ark.intel.com/products/27107/Intel-Celeron-D-Processor-320-(256K-Cache-2_40-GHz-533-MHz-FSB),,125,112,1.25,1.4
9,"2014-11-17 00:01:26.929046","2014-11-17 00:01:26.929046",9,2,,3,,4,2,,325,,2530,,1,1,73,http://ark.intel.com/products/27108/Intel-Celeron-D-Processor-325-(256K-Cache-2_53-GHz-533-MHz-FSB),,125,112,1.25,1.4
10,"2014-11-17 00:01:26.951261","2014-11-17 00:01:26.951261",9,2,,3,,4,2,,325J,,2530,,1,1,84,http://ark.intel.com/products/27110/Intel-Celeron-D-Processor-325J-(256K-Cache-2_53-GHz-533-MHz-FSB),,125,112,1.25,1.4
11,"2014-11-17 00:01:26.974090","2014-11-17 00:01:26.974090",9,2,,3,,4,2,,326,,2530,,1,1,84,http://ark.intel.com/products/27111/Intel-Celeron-D-Processor-326-(256K-Cache-2_53-GHz-533-MHz-FSB),,125,112,1.25,1.4
12,"2014-11-17 00:01:26.995734","2014-11-17 00:01:26.995734",9,2,,3,,4,2,,330,,2660,,1,1,73,http://ark.intel.com/products/27112/Intel-Celeron-D-Processor-330-(256K-Cache-2_66-GHz-533-MHz-FSB),,125,112,1.25,1.4
13,"2014-11-17 00:01:27.018634","2014-11-17 00:01:27.018634",9,2,,3,,4,2,,330J,,2660,,1,1,84,http://ark.intel.com/products/27114/Intel-Celeron-D-Processor-330J-(256K-Cache-2_66-GHz-533-MHz-FSB),,125,112,1.25,1.4
14,"2014-11-17 00:01:27.039080","2014-11-17 00:01:27.039080",9,2,,3,,4,2,,331,,2660,,1,1,84,http://ark.intel.com/products/27115/Intel-Celeron-D-Processor-331-(256K-Cache-2_66-GHz-533-MHz-FSB),,125,112,1.25,1.4
15,"2014-11-17 00:01:27.062386","2014-11-17 00:01:27.062386",9,2,,3,,4,2,,335J,,2800,,1,1,84,http://ark.intel.com/products/27118/Intel-Celeron-D-Processor-335J-(256K-Cache-2_80-GHz-533-MHz-FSB),,125,112,1.25,1.4
16,"2014-11-17 00:01:27.142737","2014-11-17 00:01:27.142737",9,2,,3,,4,2,,336,,2800,,1,1,84,http://ark.intel.com/products/27119/Intel-Celeron-D-Processor-336-(256K-Cache-2_80-GHz-533-MHz-FSB),,125,112,1.25,1.4
17,"2014-11-17 00:01:27.165279","2014-11-17 00:01:27.165279",9,2,,3,,4,2,,340,,2930,,1,1,73,http://ark.intel.com/products/27120/Intel-Celeron-D-Processor-340-(256K-Cache-2_93-GHz-533-MHz-FSB),,125,112,1.25,1.4
18,"2014-11-17 00:01:27.188150","2014-11-17 00:01:27.188150",9,2,,3,,4,2,,340J,,2930,,1,1,84,http://ark.intel.com/products/27121/Intel-Celeron-D-Processor-340J-(256K-Cache-2_93-GHz-533-MHz-FSB),,125,112,1.25,1.4
19,"2014-11-17 00:01:27.208418","2014-11-17 00:01:27.208418",9,2,,3,,4,2,,345,,3060,,1,1,73,http://ark.intel.com/products/27123/Intel-Celeron-D-Processor-345-(256K-Cache-3_06-GHz-533-MHz-FSB),,125,112,1.25,1.4
20,"2014-11-17 00:01:27.228689","2014-11-17 00:01:27.228689",9,2,,3,,4,2,,345J,,3060,,1,1,84,http://ark.intel.com/products/27124/Intel-Celeron-D-Processor-345J-(256K-Cache-3_06-GHz-533-MHz-FSB),,125,112,1.25,1.4
21,"2014-11-17 00:01:27.251224","2014-11-17 00:01:27.251224",9,2,,3,,4,2,,346,,3060,,1,1,84,http://ark.intel.com/products/27125/Intel-Celeron-D-Processor-346-(256K-Cache-3_06-GHz-533-MHz-FSB),,125,112,1.25,1.4
22,"2014-11-17 00:01:27.272903","2014-11-17 00:01:27.272903",9,2,,3,,4,2,,350,,3200,,1,1,73,http://ark.intel.com/products/27126/Intel-Celeron-D-Processor-350-(256K-Cache-3_20-GHz-533-MHz-FSB),,125,112,1.25,1.4
23,"2014-11-17 00:01:27.293688","2014-11-17 00:01:27.293688",9,2,,3,,4,2,,350J,,3200,,1,1,73,http://ark.intel.com/products/27127/Intel-Celeron-D-Processor-350350J-(256K-Cache-3_20-GHz-533-MHz-FSB),,125,112,1.25,1.4
24,"2014-11-17 00:01:27.316604","2014-11-17 00:01:27.316604",9,2,,3,,4,2,,351,,3200,,1,1,84,http://ark.intel.com/products/27128/Intel-Celeron-D-Processor-351-(256K-Cache-3_20-GHz-533-MHz-FSB),,125,112,1.25,1.4
25,"2014-11-17 00:01:27.338452","2014-11-17 00:01:27.338452",9,2,,3,,4,2,,355,,3330,,1,1,84,http://ark.intel.com/products/27130/Intel-Celeron-D-Processor-355-(256K-Cache-3_33-GHz-533-MHz-FSB),,125,112,1.25,1.4
26,"2014-11-17 00:01:27.381180","2014-11-17 00:01:27.381180",9,2,,4,,5,2,,356,,3330,,1,1,86,http://ark.intel.com/products/27131/Intel-Celeron-D-Processor-356-(512K-Cache-3_33-GHz-533-MHz-FSB),,188,81,1.25,1.325
27,"2014-11-17 00:01:27.400815","2014-11-17 00:01:27.400815",9,2,,4,,5,2,,360,,3460,,1,1,65,http://ark.intel.com/products/27132/Intel-Celeron-D-Processor-360-(512K-Cache-3_46-GHz-533-MHz-FSB),,188,81,1.25,1.325
28,"2014-11-17 00:01:27.442228","2014-11-17 00:01:27.442228",9,3,,5,,5,2,,310,,1200,,1,1,24.5,http://ark.intel.com/products/27138/Intel-Celeron-M-Processor-310-(512K-Cache-1_20-GHz-400-MHz-FSB),,77,83,,1.356
29,"2014-11-17 00:01:27.462385","2014-11-17 00:01:27.462385",9,3,,5,,5,2,,330,,1400,,1,1,24.5,http://ark.intel.com/products/27140/Intel-Celeron-M-Processor-330-(512K-Cache-1_40-GHz-400-MHz-FSB),,77,83,,1.356
30,"2014-11-17 00:01:27.484997","2014-11-17 00:01:27.484997",9,3,,5,,5,2,,340,,1500,,1,1,24.5,http://ark.intel.com/products/27141/Intel-Celeron-M-Processor-340-(512K-Cache-1_50-GHz-400-MHz-FSB),,77,83,,1.356
31,"2014-11-17 00:01:27.518347","2014-11-17 00:01:27.518347",9,3,,6,,3,2,,350,,1300,,1,1,21,http://ark.intel.com/products/27142/Intel-Celeron-M-Processor-350-(1M-Cache-1_30-GHz-400-MHz-FSB),,144,87,,1.26
32,"2014-11-17 00:01:27.538306","2014-11-17 00:01:27.538306",9,3,,6,,3,2,,360,,1400,,1,1,21,http://ark.intel.com/products/27143/Intel-Celeron-M-Processor-360-(1M-Cache-1_40-GHz-400-MHz-FSB),,144,87,,
33,"2014-11-17 00:01:27.558462","2014-11-17 00:01:27.558462",9,3,,6,,3,2,,380,,1600,,1,1,21,http://ark.intel.com/products/27146/Intel-Celeron-M-Processor-380-(1M-Cache-1_60-GHz-400-MHz-FSB),,144,87,1.004,1.292
34,"2014-11-17 00:01:27.580314","2014-11-17 00:01:27.580314",9,3,,6,,3,2,,390,,1700,,1,1,21,http://ark.intel.com/products/27147/Intel-Celeron-M-Processor-390-(1M-Cache-1_70-GHz-400-MHz-FSB),,144,87,1.004,1.292
35,"2014-11-17 00:01:27.611632","2014-11-17 00:01:27.611632",9,3,,7,,3,2,,410,,1460,,1,1,27,http://ark.intel.com/products/27148/Intel-Celeron-M-Processor-410-(1M-Cache-1_46-GHz-533-MHz-FSB),,151,90,1,1.3
36,"2014-11-17 00:01:27.632430","2014-11-17 00:01:27.632430",9,3,,7,,3,2,,420,,1600,,1,1,27,http://ark.intel.com/products/27149/Intel-Celeron-M-Processor-420-(1M-Cache-1_60-GHz-533-MHz-FSB),,151,90,1,1.3
37,"2014-11-17 00:01:27.656233","2014-11-17 00:01:27.656233",9,3,,7,,3,2,,430,,1730,,1,1,27,http://ark.intel.com/products/27150/Intel-Celeron-M-Processor-430-(1M-Cache-1_73-GHz-533-MHz-FSB),,151,90,1,1.3
38,"2014-11-17 00:01:27.676503","2014-11-17 00:01:27.676503",9,3,,7,,3,2,,450,,2000,,1,1,27,http://ark.intel.com/products/27152/Intel-Celeron-M-Processor-450-(1M-Cache-2_00-GHz-533-MHz-FSB),,151,90,1,1.3
39,"2014-11-17 00:01:27.695606","2014-11-17 00:01:27.695606",9,3,,5,,5,2,,333,,900,,1,1,7,http://ark.intel.com/products/27156/Intel-Celeron-M-Processor-ULV-333-(512K-Cache-900-MHz-400-MHz-FSB),,77,83,,1.004
and several thousand additional lines of this sort
.zipfrom some external link. Sorry. You can have a look at this guide for how to prune your code for this purpose. Especially it would be nice to see, how you try to plot that. Like this, we do not have to code all thepgfplotsstuff for you. – LaRiFaRi Jun 12 '15 at 13:40