Need to make a quad chart that puts 4 small pages in one page within an article document

Question

EDIT: See end of question.

I need to maintain the same outer margins that are defined for the rest of the document, and include a title for the quad chart. Text in one quad shouldn't flow into the other quads or I would have used multicols with horizontal lines. Someone suggested the following in a similar question, but I wasn't sure on how to implement it.

\newflowframe{.45\textwidth}{.45\textheight}{0pt}{.55\textheight}
\newflowframe{.45\textwidth}{.45\textheight}{.55\textwidth}{.55\textheight}
\newflowframe{.45\textwidth}{.45\textheight}{0pt}{0pt}
\newflowframe{.45\textwidth}{.45\textheight}{.55\textwidth}{0pt}

It would be nice if I could control the inner quad margins to use the maximal area possible without detracting from readability.

Working example, sorry about verbose preamble:

%----------------------------------------------------------------------------------------
%   PREAMBLE
%----------------------------------------------------------------------------------------

\documentclass[12pt, paper=letter]{article}

%----------------------------------------------------------------------------------------
%   REQUIRED PACKAGES
%----------------------------------------------------------------------------------------

\usepackage[
nochapters, % Turn off chapters since this is an article        
beramono, % Use the Bera Mono font for monospaced text (\texttt)
eulermath,% Use the Euler font for mathematics
pdfspacing, % Makes use of pdftex’ letter spacing capabilities via the microtype package
dottedtoc % Dotted lines leading to the page numbers in the table of contents
]{classicthesis} % The layout is based on the Classic Thesis style

\usepackage{arsclassica} % Modifies the Classic Thesis package

\usepackage[T1]{fontenc} % Use 8-bit encoding that has 256 glyphs

\usepackage[utf8]{inputenc} % Required for including letters with accents

\usepackage{graphicx} % Required for including images
\graphicspath{{Figures/}} % Set the default folder for images

\usepackage{enumitem} % Required for manipulating the whitespace between and within lists

\usepackage{lipsum} % Used for inserting dummy 'Lorem ipsum' text into the template

\usepackage{subfig} % Required for creating figures with multiple parts (subfigures)

\usepackage{amsmath,amssymb,amsthm} % For including math equations, theorems, symbols, etc

\usepackage{varioref} % More descriptive referencing

%----------------------------------------------------------------------------------------
%   THEOREM STYLES
%---------------------------------------------------------------------------------------

\theoremstyle{definition} % Define theorem styles here based on the definition style (used for definitions and examples)
\newtheorem{definition}{Definition}

\theoremstyle{plain} % Define theorem styles here based on the plain style (used for theorems, lemmas, propositions)
\newtheorem{theorem}{Theorem}

\theoremstyle{remark} % Define theorem styles here based on the remark style (used for remarks and notes)

%----------------------------------------------------------------------------------------
%   HYPERLINKS
%---------------------------------------------------------------------------------------

\hypersetup{
%draft, % Uncomment to remove all links (useful for printing in black and white)
colorlinks=true, breaklinks=true, bookmarks=true,bookmarksnumbered,
urlcolor=webbrown, linkcolor=RoyalBlue, citecolor=webgreen, % Link colors
pdftitle={}, % PDF title
pdfauthor={\textcopyright}, % PDF Author
pdfsubject={}, % PDF Subject
pdfkeywords={}, % PDF Keywords
pdfcreator={pdfLaTeX}, % PDF Creator
pdfproducer={LaTeX with hyperref and ClassicThesis} % PDF producer
}

\usepackage[english]{babel}
\usepackage[utf8]{inputenc}
\usepackage{amsmath}
\usepackage{graphicx}
\usepackage[colorinlistoftodos]{todonotes}
\usepackage{lipsum}
\usepackage{etoolbox}
\patchcmd{\thebibliography}{\section*}{\section}{}{}
%\usepackage[superscript,biblabel]{cite}
\usepackage{multirow}
\usepackage{float}
\usepackage{unicode-math}
\usepackage{tikz}
%\usepackage[toc]{multitoc}
\usepackage{soul}
%\renewcommand*{\multicolumntoc}{2}
\setlength{\columnseprule}{0.5pt}
\usepackage{geometry}
\geometry{top = 1 in, bottom = 1 in, left = 1 in, right = 1 in}
\usepackage{tabularx,ragged2e,booktabs}
\usepackage[font = small]{caption}
\usepackage{multicol,enumitem,caption,graphicx}
\captionsetup[figure]{
  font=small,% 10pt
  labelsep=endash
}
\usepackage{pdfpages}
\usepackage{hyperref}
\usepackage{xcolor}
\hypersetup{
    colorlinks,
    linkcolor={blue!50!black},
    citecolor={cyan!50!black},
    urlcolor={blue!80!black}
}

\usepackage{fontspec}
\setmainfont{Times New Roman}
\newfontfamily{\titlefont}{Arial}
\newfontfamily{\headingfont}{Arial}

\linespread{2}

\newcommand{\heading}[1]{%
  \par
  {\large\headingfont #1\par}% 12pt
  \vspace{-\baselineskip}
}


%----------------------------------------------------------------------------------------
%   HEADERS
%----------------------------------------------------------------------------------------

\renewcommand{\sectionmark}[1]{\markright{\spacedlowsmallcaps{#1}}} % The header for all pages (oneside) or for even pages (twoside)
%\renewcommand{\subsectionmark}[1]{\markright{\thesubsection~#1}} % Uncomment when using the twoside option - this modifies the header on odd pages
\lehead{\mbox{\llap{\small\thepage\kern1em\color{halfgray} \vline}\color{halfgray}\hspace{0.5em}\rightmark\hfil}} % The header style

\pagestyle{scrheadings} % Enable the headers specified in this block


%----------------------------------------------------------------------------------------
%   TITLEPAGE
%----------------------------------------------------------------------------------------

\title{\normalfont\spacedallcaps{Title}}

\author{\spacedlowsmallcaps{subtitle}}

%\date{\spacedlowsmallcaps{PI: Michael Chapiro}}

\begin{document}

\maketitle

\setcounter{tocdepth}{4}

%\tableofcontents %might need to make multi-column later to not fill more than a page.

%\vspace{1 cm}

%-------------------------------------------------------------------------------  
\lipsum[1-5]
\clearpage

%Quadchart goes here

\end{document}

EDIT: I missed the attached document detailing other format requirements. The document specifying the format is on the last two pages of the Broad Agency Announcement, and here are screenshots:

I've also found the two images, but example images would be fine: