\documentclass{article}
\usepackage{tkz-graph}
\usetikzlibrary{arrows.meta}
\begin{document}
\begin{tikzpicture}
\SetGraphUnit{2}
\renewcommand*{\VertexLineColor}{white}
\renewcommand*{\VertexLightFillColor}{red}
\renewcommand*{\VertexLineWidth}{1pt}
\GraphInit[vstyle=Welsh]
\Vertices{circle}{1,2,3,4,5,6}
\AddVertexColor{blue}{5,1}
\SetUpEdge[style={-{Straight Barb[length=1mm,width=1.2mm]}, thick},color=red]
\foreach \v [count=\vi from 2] in {1,...,5}{
\foreach \vv in {\vi,...,6}{\Edge(\v)(\vv)};
};
\end{tikzpicture}
\end{document}
gives:

Addendum:
Solution for your request in one of your comment:
\documentclass{article}
\usepackage{tkz-graph}
\usetikzlibrary{arrows.meta}
\begin{document}
\begin{tikzpicture}
\SetGraphUnit{2}
\renewcommand*{\VertexLineColor}{white}
\renewcommand*{\VertexLightFillColor}{red}
\renewcommand*{\VertexLineWidth}{1pt}
\GraphInit[vstyle=Welsh]
\SetVertexNoLabel % <-- added
\Vertices{circle}{1,2,3,4,5,6}
\SetUpEdge[style={-{Straight Barb[length=1mm,width=1.2mm]}, thick},color=red]
\foreach \v [count=\vi from 2] in {1,...,5}
{
\foreach \vv in {\vi,...,6}{\Edge(\v)(\vv)};
};
\SetVertexLabel
\Vertices{circle}{A,B,C,D,E,F} % <-- added
\AddVertexColor{blue}{1,5}% <-- moved here
\end{tikzpicture}
\end{document}
Addendum (2):
solution for naming of vertices without their double drawing:
\documentclass{article}
\usepackage{tkz-graph}
\usetikzlibrary{arrows.meta}
\begin{document}
\begin{tikzpicture}
\SetGraphUnit{2}
\renewcommand*{\VertexLineColor}{white}
\renewcommand*{\VertexLightFillColor}{red}
\renewcommand*{\VertexLineWidth}{1pt}
\GraphInit[vstyle=Welsh]
\Vertices{circle}{A,B,C,D,E,F}
\SetUpEdge[style={-{Straight Barb[length=1mm,width=1.2mm]}, thick},color=red]
\foreach \v [remember=\v as \vi (initially A)] in {B,...,F}
{
\foreach \vv in {\v,...,F}{\Edge(\vi)(\vv)};
};
\AddVertexColor{blue}{A,E}
\end{tikzpicture}
\end{document}
\documentclass{...}and end with\end{document}. As it is, it gives errors (undefined control sequence ...). Welcome to TeX.SE! – Zarko May 18 '17 at 17:38tkz-graph(which is based ontikz) . Next time this you should do yourself ... – Zarko May 18 '17 at 18:59