This question is related to Two letter variable names and Multiple letters without spacing in Math [duplicate], but it seems to me that the answers to these questions do not fully solve my problem.
In the example
\documentclass{article}
\usepackage{lmodern}
\usepackage{amsmath}
\begin{document}
\par (1) $\left\{ S, Y, Z \right\}$
\par (2) $\left\{ Satz, Y, Z \right\}$
\par (3) $\left\{ \text{\textit{Satz}}, \text{\textit{Y}}, \text{\textit{Z}} \right\}$
\par (4) $\left\{ \mathit{Satz}, \mathit{Y}, \mathit{Z} \right\}$
\end{document}
the result
of (3) \text{\textit{Satz}} and (4) \mathit{Satz} is satisfactory with respect to the inter-word spacing of the letters. In (1) and (2), however, the spacing between Y and , looks better. Is there a way to combine both advantages without the need for manual kerning?
Please note that, although Y is a single-letter variable name, similar problems would arise if a multi-letter variable name ended with Y.

$\left\{ \mathit{Satz}, Y, Z \right\}$and avoid to many multiletter variables. Even if it works more or less with \mathit, it is confusing and -- as you see -- the spacing is not really adapted to them. – Ulrike Fischer Nov 22 '17 at 17:52\{\mathit{SatZ}, Z,Y\}and you'll see this is only an optical illusion. – Bernard Nov 22 '17 at 17:53SatzYin which your advice would not help. – Matthias Nov 22 '17 at 17:54Yand,in the options (2) and (3) is an optical illusion? Based on a measuring the distance in the image I do not think so. – Matthias Nov 22 '17 at 19:13