This solution is exactly what I'm going for, but unfortunately the tabularray package removes the ability to use multicolumn and I cannot therefore get any of the solutions to work.
I tried just replacing the multicolumn command with Tabularray's \SetCell, but that was unsuccessful.
Would love some assist modifying the original solution or something different to achieve the same result (ideally still using tabularray as the base, but if I really can't, I can consider switching to other table packages for this table).
Here is an example table with the cell to strike through indicated.
\documentclass{article}
\usepackage{tabularray}
\begin{document}
\begin{tblr}{
colspec = {Q[l,m,2in]*{2}{Q[c,m]}},
hlines,
vlines
}
Testing a cell & Test & More text\
Another row & & \
\SetRow{ht=1.5in}{Strike this cell out with an X\from bottom-left to top-right\and top-left to bottom-right\may have more than one row\or altered height} & & \
\end{tblr}
\end{document}


