May be this solution with tizk-cd can help. The syntaxis is very much the same as xymatrix. The basic xy-command \ar and the directions [u],...,[r] are replaced by \arrow and {u},{d},{l},{r} in curly brackets, respectively.
\documentclass[a4paper,10pt]{article}
\usepackage[utf8]{inputenc}
%\usepackage{tikz}
\usepackage{tikz-cd}
\begin{document}
\begin{tikzcd}
& & & & & & X_1\times_Y X_2\\
& & X_1 \times_Z X_2\arrow{dl}\arrow{rr}\arrow{dd} & & X_1\arrow{dd}\arrow{dl} & &\\
& Y\times_Z Y\arrow{rr}\arrow{dd} & & Y\arrow{dd} & & & \\
& & X_2\arrow{dl} \arrow{rr} & & Y\arrow{dl} & & \\
& Y\arrow{rr} & & Z & & & Y
\arrow
[to path={..controls +(-10,-1) and (-6,-3) .. (\tikztotarget)}]{uulllll}
\end{tikzcd}
\end{document}

Another possibility is
\begin{tikzcd}
& & & & & & X_1\times_Y X_2\\
& & X_1 \times_Z X_2\arrow{dl}\arrow{rr}\arrow{dd} & & X_1\arrow{dd}\arrow{dl} & &\\
& Y\times_Z Y\arrow{rr}\arrow{dd} & & Y\arrow{dd} & & & \\
& & X_2\arrow{dl} \arrow{rr} & & Y\arrow{dl} & & \\
& Y\arrow{rr} & & Z & & & Y
\arrow[to path={ (4.9,-2.8)--(4.9,-3.2)--(-5.4,-3.2)
--(-5.4,0)--(\tikztotarget)}]{uulllll}
\end{tikzcd}
Another one
\begin{tikzcd}
& & & & & & X_1\times_Y X_2\\
& & X_1 \times_Z X_2\arrow{dl}\arrow{rr}\arrow{dd} & & X_1\arrow{dd}\arrow{dl} & &\\
& Y\times_Z Y\arrow{rr}\arrow{dd} & & Y\arrow{dd} & & & \\
& & X_2\arrow{dl} \arrow{rr} & & Y\arrow{dl} & & \\
& Y\arrow{rr} & & Z & & & Y
\arrow[to path={ (4.9,-2.8)--(4.9,-3.2)--(-5.6,-3.2)
--(-5.6,-.6)--(\tikztotarget)}]{uulllll}
\end{tikzcd}
