OR3A4

Olfactory receptor 3A4 is a protein that in humans is encoded by the OR3A4 gene.[3]

OR3A4P
Identifiers
AliasesOR3A4P, OLFRA05, OLFRA06, OR17-13, OR17-16, OR17-24, OR17-25, OR24, OR25, OR3A4, OR3A5P, olfactory receptor family 3 subfamily A member 4 pseudogene
External IDsGeneCards: OR3A4P; OMA:OR3A4P - orthologs
Orthologs
SpeciesHumanMouse
Entrez

390756

n/a

Ensembl

ENSG00000180068

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UniProt

n
a

n/a

RefSeq (mRNA)

NM_001005334

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 17: 3.31 – 3.31 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000180068 – Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: OR3A4 olfactory receptor, family 3, subfamily A, member 4".

Further reading
  • Ben-Arie N, Lancet D, Taylor C, et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum. Mol. Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088.
  • Glusman G, Clifton S, Roe B, Lancet D (1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity". Genomics. 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID 8921386.
  • Glusman G, Sosinsky A, Ben-Asher E, et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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